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, 3-methyladenine as well as LY294002) would not prevent piling up associated with neem-induced LC3-II inside most cancers cells. Silencing regarding ATG5 or even Beclin-1 even more improved neem-induced cellular death. Phosphoinositide 3-kinase (PI3K) or autophagy inhibitors improved neem-induced caspase-3 initial and also inhibition involving […] View
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