@brickweasel09
2 years ago
Furthermore, PELP1 has been hyper-phosphorylated with it’s CDK phosphorylation site ABT-737 in vitro , indicating a good autocrine never-ending loop concerning the CDK-cyclin D1-PELP1 axis to promote mammary tumorigenesis. Management of PELP1 Tg mice which has a KDM1 inhibitor substantially decreased PELP1-driven hyperbranching, solved […] View