@brickweasel09
Active 2 years, 3 months ago
Furthermore, PELP1 has been hyper-phosphorylated with it’s CDK phosphorylation site ABT-737 in vitro , indicating a good autocrine never-ending loop concerning the CDK-cyclin D1-PELP1 axis to promote mammary tumorigenesis. Management of PELP1 Tg mice which has a KDM1 inhibitor substantially decreased PELP1-driven hyperbranching, solved […] View
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